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      <image:title>Blog - Should you target a biomarker-positive population in your clinical trial, or simply track it? - Make it stand out</image:title>
      <image:caption>Sample Size Ratios as a Function of the Prevalence of Marker-Positive Patients Source</image:caption>
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      <image:caption>Waterfall plot for RET fusion partner assessment in the phase 1 trial of a RET inhibitor. Notice the dashed horizontal line on the graph that separates stable disease (above the line) from partial response (below the line).</image:caption>
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      <image:caption>MAPK pathway inhibition, measured by DUSP6, correlates with KRAS G12C alkylation. Tran et al Anal. Chem. 2023, 95, 11, 4834–4839.</image:caption>
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      <image:caption>Desai et al 2024 Nature Medicine volume 30, pages 271–278 (2024)</image:caption>
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